CCL4 anticorps (AA 24-92)

N° du produit ABIN7978727

Cet anticorps anti-CCL4 Polyclonal Lapin (ABIN7978727) détecte spécifiquement CCL4 dans WB et IHC. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour CCL4 anticorps (AA 24-92) (ABIN7978727)

Antigène: CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Détail du produit anti-CCL4 anticorps

Épitope: AA 24-92

Fonction: Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Rat CCL4 shares 80%,86% amino acid (aa) sequences identity with human,mouse CCL4,respectively.

Attributs du produit: Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody. Tested in IHC, WB applications. This antibody reacts with Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived rat CCL4 recombinant protein (Position: A24-N92). Rat CCL4 shares 80% and 86% amino acid (aa) sequences identity with human and mouse CCL4, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Rat

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CCL4

Antigène: CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Autre désignation: CCL4

Sujet:

Background: Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines (11, 14).

Gene Full Name: C-C motif chemokine ligand 4

Sequence Similarities: Belongs to the Wnt family.

Poids moléculaire: 36 kDa

ID gène: 116637

UniProt: P50230