CCL7 anticorps (AA 24-97) (APC)

N° du produit ABIN7978768

L’anticorps anti-CCL7 Polyclonal Lapin est utilisé pour la détection de CCL7 dans des échantillons de Souris. Il a été validé pour FACS.

Aperçu rapide pour CCL7 anticorps (AA 24-97) (APC) (ABIN7978768)

Antigène: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL7 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-CCL7 anticorps (APC)

Épitope: AA 24-97

Fonction: Anti-MCP3/CCL7 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Mouse MCP3 shares 60%,95% amino acid (aa) sequences identity with human,rat MCP3,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse MCP3 recombinant protein (Position: Q24-P97). Mouse MCP3 shares 60% and 95% amino acid (aa) sequences identity with human and rat MCP3, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CCL7

Antigène: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Autre désignation: CCL7

Sujet:

Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

Gene Full Name: C-C motif chemokine ligand 7

Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

ID gène: 20306

UniProt: Q03366