CCR10 anticorps (N-Term) (Fluoro647)

N° du produit ABIN7978825

L’anticorps anti-CCR10 Polyclonal Lapin est utilisé pour la détection de CCR10 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour CCR10 anticorps (N-Term) (Fluoro647) (ABIN7978825)

Antigène: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR10 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-CCR10 anticorps (Fluoro647)

Épitope: N-Term

Fonction: Anti-GPR2/CCR10 Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human GPR2/CCR10, which shares 81% and 85.7% amino acid (aa) sequence identity with mouse and rat GPR2/CCR10, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CCR10

Antigène: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Autre désignation: CCR10

Sujet:

Background: C-C chemokine receptor type 10 is a protein that in humans is encoded by the CCR10 gene. It is mapped to 17q21.2. Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27, MIM 604833), CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation.

Gene Full Name: C-C motif chemokine receptor 10

ID gène: 2826

UniProt: P46092