CCR6 anticorps (C-Term) (Cy3)

N° du produit ABIN7979026

L’anticorps anti-CCR6 Polyclonal Lapin est utilisé pour la détection de CCR6 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour CCR6 anticorps (C-Term) (Cy3) (ABIN7979026)

Antigène: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR6 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-CCR6 anticorps (Cy3)

Épitope: C-Term

Fonction: Anti-CCR6/CCR6 Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat,mouse sequences by two amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6, different from the related rat and mouse sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CCR6

Antigène: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Autre désignation: CCR6

Sujet:

Background: CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca (2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.

Gene Full Name: C-C motif chemokine receptor 6

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

ID gène: 1235

UniProt: P51684

Pathways: cAMP Metabolic Process