CCR6 anticorps (C-Term)

N° du produit ABIN7979035

L’anticorps anti-CCR6 Polyclonal Lapin est utilisé pour la détection de CCR6 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour CCR6 anticorps (C-Term) (ABIN7979035)

Antigène: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR6 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-CCR6 anticorps

Épitope: C-Term

Fonction: Anti-CCR6/CCR6 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat,mouse sequences by two amino acids.

Attributs du produit: Anti-CCR6/CCR6 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6, different from the related rat and mouse sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CCR6

Antigène: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Autre désignation: CCR6

Sujet:

Background: CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca (2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.

Gene Full Name: C-C motif chemokine receptor 6

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

Poids moléculaire: 120 kDa

ID gène: 1235

UniProt: P51684

Pathways: cAMP Metabolic Process