CXCR1 anticorps (N-Term) (HRP)

N° du produit ABIN7979251

L’anticorps anti-CXCR1 Polyclonal Lapin est utilisé pour la détection de CXCR1 dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour CXCR1 anticorps (N-Term) (HRP) (ABIN7979251)

Antigène: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-CXCR1 anticorps (HRP)

Épitope: N-Term

Fonction: Anti-CXCR1 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CXCR1

Antigène: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Autre désignation: CXCR1

Sujet:

Background: CXCR1 (Chemokine,CXC Motif, Receptor 1), also known as IL8RA or IL8R1, is a chemokine receptor. IL8RA is its human gene. Morris et al. (1992) mapped the IL8RA gene to chromosome 2q35. Hartl et al. (2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic mechanism in CF and other neutrophilic airway diseases. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

Gene Full Name: C-X-C motif chemokine receptor 1

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

ID gène: 3577

UniProt: P25024

Pathways: cAMP Metabolic Process