CXCR3 anticorps (AA 1-368) (FITC)

N° du produit ABIN7979316

Cet anticorps Lapin Polyclonal détecte spécifiquement CXCR3 dans FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour CXCR3 anticorps (AA 1-368) (FITC) (ABIN7979316)

Antigène: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR3 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-CXCR3 anticorps (FITC)

Épitope: AA 1-368

Fonction: Anti-CXCR3 Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human CXCR3 shares 86% amino acid (aa) sequence identity with both mouse,rat CXCR3.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CXCR3 recombinant protein (Position: M1-L368). Human CXCR3 shares 86% amino acid (aa) sequence identity with both mouse and rat CXCR3.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CXCR3

Antigène: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Autre désignation: CXCR3

Sujet:

Background: Chemokine receptor CXCR3 is a Galphai protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183. It is mapped to Xq13.1. CXCR3 is expressed on malignant B cells from chronic lymphoproliferative disorders, particularly in patients with CLL, and represents a fully functional receptor involved in chemotaxis of malignant B lymphocytes. It is found that in the absence of known etiologic agents, CXCR3 represents a novel target for therapeutic interference early in type 1 diabetes. CXCR3 signaling is associated with MG pathogenesis and proposed that and CXCR3 may serve as novel drug targets to treat MG. CXCR3A and CXCR3B are involved in the chemotactic and vascular effects of CXCL4L1.

Gene Full Name: C-X-C motif chemokine receptor 3

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

ID gène: 2833

UniProt: P49682