C10orf2 anticorps (AA 39-635) (Fluoro594)

N° du produit ABIN7979975

Cet anticorps anti-C10orf2 Polyclonal Lapin conjugué à Fluoro594 (ABIN7979975) détecte spécifiquement C10orf2 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour C10orf2 anticorps (AA 39-635) (Fluoro594) (ABIN7979975)

Antigène: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C10orf2 est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-C10orf2 anticorps (Fluoro594)

Épitope: AA 39-635

Fonction: Anti-Twinkle/TWNK Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human Twinkle,TWNK shares 87.8% amino acid (aa) sequence identity with mouse Twinkle,TWNK.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Twinkle/TWNK recombinant protein (Position: R39-K635). Human Twinkle/TWNK shares 87.8% amino acid (aa) sequence identity with mouse Twinkle/TWNK.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur C10orf2

Antigène: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Autre désignation: TWNK

Sujet:

Background: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: twinkle mtDNA helicase

ID gène: 56652

UniProt: Q96RR1