Claudin 3 anticorps (AA 101-220) (HRP)

N° du produit ABIN7980484

L’anticorps anti-Claudin 3 Monoclonal Souris est utilisé pour la détection de Claudin 3 dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour Claudin 3 anticorps (AA 101-220) (HRP) (ABIN7980484)

Antigène: Claudin 3 (CLDN3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Claudin 3 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4C7D2

Détail du produit anti-Claudin 3 anticorps (HRP)

Épitope: AA 101-220

Fonction: Anti-Claudin 3/CLDN3 Antibody (monoclonal, 4C7D2) HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Claudin 3/CLDN3 recombinant protein (Position: A101-V220).

Isotype: IgG2b

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Claudin 3

Antigène: Claudin 3 (CLDN3)

Autre désignation: CLDN3

Sujet:

Background: Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Gene Full Name: claudin 3

ID gène: 1365

UniProt: O15551

Pathways: Hepatitis C