Claudin 5 anticorps (C-Term) (Biotin)

N° du produit ABIN7980489

Cet anticorps Lapin Polyclonal détecte spécifiquement Claudin 5 dans IHC, WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Claudin 5 anticorps (C-Term) (Biotin) (ABIN7980489)

Antigène: Claudin 5 (CLDN5)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 5 est conjugé à/à la Biotin

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Détail du produit anti-Claudin 5 anticorps (Biotin)

Épitope: C-Term

Fonction: Anti-Claudin 5/CLDN5 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by three amino acids,from the related rat sequence by four amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5, different from the related mouse sequence by three amino acids and from the related rat sequence by four amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Claudin 5

Antigène: Claudin 5 (CLDN5)

Autre désignation: CLDN5

Sujet:

Background: Claudin-5 (CLDN5) also known as BEC1, is a protein that in humans is encoded by the CLDN5 gene. By use of yeast artificial chromosomes, Claudin-5 is localized between polymorphic markers D22S944 and D22S941 on chromosome 22q11, both of which are deleted in more than 80 % of VCFS patients. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. What's more, it plays a major role in tight junction-specific obliteration of the intercellular space.

Gene Full Name: claudin 5

ID gène: 7122

UniProt: O00501

Pathways: Hepatitis C