CLPB anticorps (AA 438-707) (Fluoro488)

N° du produit ABIN7980568

L’anticorps anti-CLPB Polyclonal Lapin est utilisé pour la détection de CLPB dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour FACS.

Aperçu rapide pour CLPB anticorps (AA 438-707) (Fluoro488) (ABIN7980568)

Antigène: CLPB (ClpB Caseinolytic Peptidase B Homolog (CLPB))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLPB est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-CLPB anticorps (Fluoro488)

Épitope: AA 438-707

Fonction: Anti-CLPB Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CLPB recombinant protein (Position: Q438-I707).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CLPB

Antigène: CLPB (ClpB Caseinolytic Peptidase B Homolog (CLPB))

Autre désignation: CLPB

Sujet:

Background: This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants.

Gene Full Name: ClpB family mitochondrial disaggregase

ID gène: 81570

UniProt: Q9H078