Factor VIII anticorps (Middle Region)
Aperçu rapide pour Factor VIII anticorps (Middle Region) (ABIN7980807)
Antigène
Voir toutes Factor VIII (F8) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
-
-
Épitope
- Middle Region
-
Fonction
- Anti-Factor VIII/F8 Antibody
-
Specificité
- No cross reactivity with other proteins.
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins
-
Attributs du produit
- Anti-Factor VIII/F8 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- A synthetic peptide corresponding to a sequence in the middle region of human Factor VIII.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
-
Précaution d'utilisation
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
-
-
- Factor VIII (F8) (Coagulation Factor VIII (F8))
-
Autre désignation
- F8
-
Sujet
-
Background: Coagulation Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). By in situ hybridization, Tantravahi et al. (1986) concluded that the F8 gene is located in the proximal part of chromosome Xq28 with probes DX13 and St14 distally located. The F8 gene encodes coagulation factor VIII, a large plasma glycoprotein that functions in the blood coagulation cascade as a cofactor for the factor IXa-dependent activation of factor X (F10). Factor VIII is activated proteolytically by a variety of coagulation enzymes, including thrombin (F2). Factor VIII is tightly associated in the blood with von Willebrand factor (VWF), which serves as a protective carrier protein for factor VIII (Toole et al., 1984, Hoyer, 1994).
Gene Full Name: coagulation factor VIII
Sequence Similarities: Belongs to the multicopper oxidase family.
-
Poids moléculaire
- 92 kDa
-
ID gène
- 2157
-
UniProt
- P00451
Antigène
-