Factor XI anticorps (AA 79-155) (Fluoro647)

N° du produit ABIN7980817

L’anticorps anti-Factor XI Polyclonal Lapin est utilisé pour la détection de Factor XI dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour Factor XI anticorps (AA 79-155) (Fluoro647) (ABIN7980817)

Antigène: Factor XI (F11) (Coagulation Factor XI (F11))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Factor XI est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-Factor XI anticorps (Fluoro647)

Épitope: AA 79-155

Fonction: Anti-FXI/F11 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FXI/F11 recombinant protein (Position: K79-Q155).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Factor XI

Antigène: Factor XI (F11) (Coagulation Factor XI (F11))

Autre désignation: F11

Sujet:

Background: Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade. Like many other coagulation factors, it is a serine protease. In humans, Factor XI is encoded by the F11 gene. This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

Gene Full Name: coagulation factor XI

ID gène: 2160

UniProt: P03951