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LAG3 anticorps (AA 210-260) (PE)

LAG3 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal PE
N° du produit ABIN748518
  • Antigène Voir toutes LAG3 Anticorps
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Épitope
    • 15
    • 14
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-260
    Reactivité
    • 87
    • 38
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 51
    • 35
    • 12
    • 4
    Lapin
    Clonalité
    • 52
    • 47
    • 1
    Polyclonal
    Conjugué
    • 53
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LAG3 est conjugé à/à la PE
    Application
    • 68
    • 36
    • 33
    • 30
    • 25
    • 22
    • 15
    • 13
    • 13
    • 10
    • 10
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
    Isotype
    IgG
    Top Product
    Discover our top product LAG3 Anticorps primaire
  • Indications d'application
    FCM(1:20-100)
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Parodi, Battaglia, Kalli, Ferrera, Conteduca, Tardito, Stringara, Ivaldi, Negrini, Borgonovo, Simonato, Traverso, Carmignani, Fenoglio, Filaci: "CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." dans: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).

  • Antigène
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Autre désignation
    Lymphocyte Activation Gene 3 (LAG3 Produits)
    Synonymes
    anticorps CD223, anticorps LAG-3, anticorps Ly66, anticorps lymphocyte activating 3, anticorps lymphocyte-activation gene 3, anticorps LAG3, anticorps Lag3
    Sujet

    Synonyms: CD223, Lymphocyte activation gene 3 protein, LAG-3, Lag3

    Background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

    ID gène
    297596
    UniProt
    Q5BK54
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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