Cyclin T1 anticorps (Middle Region) (Fluoro594)

N° du produit ABIN7982235

Cet anticorps Souris Monoclonal détecte spécifiquement Cyclin T1 dans FACS. Il présente une réactivité avec des échantillons de Humain et Singe.

Aperçu rapide pour Cyclin T1 anticorps (Middle Region) (Fluoro594) (ABIN7982235)

Antigène: Cyclin T1 (CCNT1)

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin T1 est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Clone: 3B7

Détail du produit anti-Cyclin T1 anticorps (Fluoro594)

Épitope: Middle Region

Fonction: Anti-Cyclin T1 Antibody (monoclonal, 3B7) Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Cyclin T1, different from the related mouse sequence by one amino acid.

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Cyclin T1

Antigène: Cyclin T1 (CCNT1)

Autre désignation: CCNT1

Sujet:

Background: Cyclin-T1 is a protein that in humans is encoded by the CCNT1 gene. This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants.

Gene Full Name: cyclin T1

ID gène: 904

UniProt: O60563