CST3 anticorps (AA 31-146) (HRP)

N° du produit ABIN7982743

L’anticorps anti-CST3 Monoclonal Souris est utilisé pour la détection de CST3 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour CST3 anticorps (AA 31-146) (HRP) (ABIN7982743)

Antigène: CST3 (Cystatin C (CST3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CST3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 4H8

Détail du produit anti-CST3 anticorps (HRP)

Épitope: AA 31-146

Fonction: Anti-Cystatin C/CST3 Antibody (monoclonal, 4H8) HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Cystatin C recombinant protein (Position: K31-A146).

Isotype: IgG2a

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CST3

Antigène: CST3 (Cystatin C (CST3))

Autre désignation: CST3

Sujet:

Background: Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

Gene Full Name: cystatin C

ID gène: 1471

UniProt: P01034