CRLF2 anticorps (AA 26-231)
Aperçu rapide pour CRLF2 anticorps (AA 26-231) (ABIN7983551)
Antigène
Voir toutes CRLF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
-
-
Épitope
- AA 26-231
-
Fonction
- Anti-CRLF2 Antibody
-
Specificité
- No cross reactivity with other proteins.
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins.
-
Attributs du produit
- Anti-CRLF2 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- E. coli-derived human CRLF2 recombinant protein (Position: A26-K231).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Western blot, 0.1-0.5 μg/mL ELISA (Cap), 1-5 μg/mL
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
-
-
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
-
Autre désignation
- CRLF2
-
Sujet
-
Background: Cytokine receptor-like factor 2 is a protein that in humans is encoded by the CRLF2 gene. This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
Gene Full Name: cytokine receptor like factor 2
-
Poids moléculaire
- 65-75 kDa
-
ID gène
- 64109
-
UniProt
- Q9HC73
Antigène
-