DBF4 anticorps (AA 295-665) (Fluoro594)

N° du produit ABIN7983802

L’anticorps anti-DBF4 Polyclonal Lapin est utilisé pour la détection de DBF4 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour DBF4 anticorps (AA 295-665) (Fluoro594) (ABIN7983802)

Antigène: DBF4 (DBF4 Homolog (DBF4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DBF4 est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-DBF4 anticorps (Fluoro594)

Épitope: AA 295-665

Fonction: Anti-DBF4 Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DBF4 recombinant protein (Position:Y295-S665).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur DBF4

Antigène: DBF4 (DBF4 Homolog (DBF4))

Autre désignation: DBF4

Sujet:

Background: Using both gain- and loss-of-function experiments, it was found that Xenopus Dbf4 inhibited canonical Wnt signaling. Depletion of endogenous Dbf4 did not disturb gastrulation movements or early organizer genes, but resulted in embryos with morphologically defective heart and eyes and suppressed cardiac markers. The function of Dbf4 in heart development appeared to be independent of its role in the cell cycle. Dbf4 interacted physically and functionally with Frodo, a context-dependent regulator of Wnt signaling.

Gene Full Name: DBF4-CDC7 kinase regulatory subunit

ID gène: 10926

UniProt: Q9UBU7

Pathways: Mitotic G1-G1/S Phases, DNA Replication