DDHD1 anticorps (AA 63-711) (Fluoro488)

N° du produit ABIN7983940

L’anticorps anti-DDHD1 Polyclonal Lapin est utilisé pour la détection de DDHD1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour DDHD1 anticorps (AA 63-711) (Fluoro488) (ABIN7983940)

Antigène: DDHD1 (DDHD Domain Containing 1 (DDHD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDHD1 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-DDHD1 anticorps (Fluoro488)

Épitope: AA 63-711

Fonction: Anti-DDHD1 Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DDHD1 recombinant protein (Position: P63-S711).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur DDHD1

Antigène: DDHD1 (DDHD Domain Containing 1 (DDHD1))

Autre désignation: DDHD1

Sujet:

Background: This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: DDHD domain containing 1

ID gène: 80821

UniProt: Q8NEL9