DOCK1 anticorps (AA 100-1732) (Biotin)

N° du produit ABIN7984570

L’anticorps anti-DOCK1 Polyclonal Lapin est utilisé pour la détection de DOCK1 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour DOCK1 anticorps (AA 100-1732) (Biotin) (ABIN7984570)

Antigène: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-DOCK1 anticorps (Biotin)

Épitope: AA 100-1732

Fonction: Anti-DOCK180/DOCK1 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DOCK180/DOCK1 recombinant protein (Position: S100-T1732).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DOCK1

Antigène: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Autre désignation: DOCK1

Sujet:

Background: Dock180, (Dedicator of cytokinesis) also known as DOCK1, is a large (~180 kDa) protein involved in intracellular signalling networks. This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

Gene Full Name: dedicator of cytokinesis 1

ID gène: 1793

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor