Desmocollin 3 anticorps (AA 87-676)

N° du produit ABIN7984965

Cet anticorps Lapin Polyclonal détecte spécifiquement Desmocollin 3 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Desmocollin 3 anticorps (AA 87-676) (ABIN7984965)

Antigène: Desmocollin 3 (DSC3)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmocollin 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Desmocollin 3 anticorps

Épitope: AA 87-676

Fonction: Anti-DSC3 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-DSC3 Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DSC3 recombinant protein (Position: L87-Q676).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Rat ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Desmocollin 3

Antigène: Desmocollin 3 (DSC3)

Autre désignation: DSC3

Sujet:

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: desmocollin 3

Poids moléculaire: 90-110 kDa

ID gène: 1825

UniProt: Q14574