Desmocollin 3 anticorps (AA 87-676) (HRP)

N° du produit ABIN7984972

L’anticorps anti-Desmocollin 3 Polyclonal Lapin est utilisé pour la détection de Desmocollin 3 dans des échantillons de Humain et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour Desmocollin 3 anticorps (AA 87-676) (HRP) (ABIN7984972)

Antigène: Desmocollin 3 (DSC3)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmocollin 3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Desmocollin 3 anticorps (HRP)

Épitope: AA 87-676

Fonction: Anti-DSC3 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DSC3 recombinant protein (Position: L87-Q676).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Desmocollin 3

Antigène: Desmocollin 3 (DSC3)

Autre désignation: DSC3

Sujet:

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: desmocollin 3

ID gène: 1825

UniProt: Q14574