Desmoglein 2 anticorps (AA 24-1020)

N° du produit ABIN7984998

Cet anticorps Souris Monoclonal détecte spécifiquement Desmoglein 2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Desmoglein 2 anticorps (AA 24-1020) (ABIN7984998)

Antigène: Desmoglein 2 (DSG2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmoglein 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Clone: 2B4D1

Détail du produit anti-Desmoglein 2 anticorps

Épitope: AA 24-1020

Fonction: Anti-Desmoglein 2/DSG2 Antibody (monoclonal, 2B4D1)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Desmoglein 2/DSG2 Antibody.(monoclonal, 2B4D1)-2. Tested in IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Desmoglein 2/DSG2 recombinant protein (Position: L24-E1020).

Isotype: IgG1

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Desmoglein 2

Antigène: Desmoglein 2 (DSG2)

Autre désignation: DSG2

Sujet:

Background: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.

Gene Full Name: desmoglein 2

Poids moléculaire: 160 kDa

ID gène: 1829

UniProt: Q14126

Pathways: Cell-Cell Junction Organization