Desmoglein 2 anticorps (C-Term) (APC)

N° du produit ABIN7985006

Cet anticorps anti-Desmoglein 2 Polyclonal Lapin conjugué à APC (ABIN7985006) détecte spécifiquement Desmoglein 2 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Desmoglein 2 anticorps (C-Term) (APC) (ABIN7985006)

Antigène: Desmoglein 2 (DSG2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 2 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-Desmoglein 2 anticorps (APC)

Épitope: C-Term

Fonction: Anti-Desmoglein 2/DSG2 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse,rat sequences by one amino acid.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Desmoglein 2, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Desmoglein 2

Antigène: Desmoglein 2 (DSG2)

Autre désignation: DSG2

Sujet:

Background: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.

Gene Full Name: desmoglein 2

Sequence Similarities: Contains 4 cadherin domains.

ID gène: 1829

UniProt: Q14126

Pathways: Cell-Cell Junction Organization