Diazepam Binding Inhibitor anticorps (AA 2-87) (Cy3)

N° du produit ABIN7985135

Cet anticorps anti-Diazepam Binding Inhibitor Polyclonal Lapin conjugué à Cy3 (ABIN7985135) détecte spécifiquement Diazepam Binding Inhibitor dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Diazepam Binding Inhibitor anticorps (AA 2-87) (Cy3) (ABIN7985135)

Antigène: Diazepam Binding Inhibitor (DBI)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Diazepam Binding Inhibitor est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-Diazepam Binding Inhibitor anticorps (Cy3)

Épitope: AA 2-87

Fonction: Anti-Diazepam Binding Inhibitor/DBI Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived human DBI recombinant protein (Position: S2-I87). Human DBI shares 77.9% amino acid (aa) sequence identity with both mouse,rat DBI.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human DBI recombinant protein (Position: S2-I87). Human DBI shares 77.9% amino acid (aa) sequence identity with both mouse and rat DBI.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Diazepam Binding Inhibitor

Antigène: Diazepam Binding Inhibitor (DBI)

Autre désignation: DBI

Sujet:

Background: Acyl-CoA-binding protein is a protein that in humans is encoded by the DBI gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: diazepam binding inhibitor, acyl-CoA binding protein

ID gène: 1622

UniProt: P07108