DPYSL2 anticorps (N-Term) (HRP)

N° du produit ABIN7985373

Cet anticorps Lapin Polyclonal détecte spécifiquement DPYSL2 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DPYSL2 anticorps (N-Term) (HRP) (ABIN7985373)

Antigène: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPYSL2 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-DPYSL2 anticorps (HRP)

Épitope: N-Term

Fonction: Anti-CRMP2/DPYSL2 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human CRMP2/DPYSL2, which shares 94.1% amino acid (aa) sequence identity with both mouse and rat CRMP2/DPYSL2.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DPYSL2

Antigène: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Autre désignation: DPYSL2

Sujet:

Background: Dihydropyrimidinase-related protein 2 is an enzyme that in humans is encoded by the DPYSL2 gene. This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: dihydropyrimidinase like 2

ID gène: 1808

UniProt: Q16555

Pathways: Regulation of Cell Size