DLG1 anticorps (AA 1-165) (Fluoro488)

N° du produit ABIN7985631

Cet anticorps Lapin Polyclonal détecte spécifiquement DLG1 dans FACS. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour DLG1 anticorps (AA 1-165) (Fluoro488) (ABIN7985631)

Antigène: DLG1 (Discs, Large Homolog 1 (DLG1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLG1 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-DLG1 anticorps (Fluoro488)

Épitope: AA 1-165

Fonction: Anti-SAP97/DLG1 Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human SAP97 shares 89.7%,84.2% amino acid (aa) sequence identity with mouse,rat SAP97,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SAP97 recombinant protein (Position: M1-A165). Human SAP97 shares 89.7% and 84.2% amino acid (aa) sequence identity with mouse and rat SAP97, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur DLG1

Antigène: DLG1 (Discs, Large Homolog 1 (DLG1))

Autre désignation: DLG1

Sujet:

Background: Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously. Mice in which the SAP97 gene has been knocked out die perinatally, have a cleft palate, and deficiencies in renal function. Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength.

Gene Full Name: discs large MAGUK scaffold protein 1

Sequence Similarities: Belongs to the MAGUK family.

ID gène: 1739

UniProt: Q12959

Pathways: Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response