DUSP1 anticorps (N-Term) (HRP)
Aperçu rapide pour DUSP1 anticorps (N-Term) (HRP) (ABIN7986449)
Antigène
Voir toutes DUSP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- Anti-MKP-1/DUSP1 Antibody HRP Conjugated
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the N-terminus of human MKP-1/DUSP1, which shares 96.3% amino acid (aa) sequence identity with both mouse and rat MKP-1/DUSP1.
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Isotype
- IgG
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Indications d'application
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))
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Autre désignation
- DUSP1
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Sujet
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Background: Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene. The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.
Gene Full Name: dual specificity phosphatase 1
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ID gène
- 1843
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UniProt
- P28562
Antigène
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