ELP3/KAT9 anticorps (C-Term) (HRP)

N° du produit ABIN7987405

L’anticorps anti-ELP3/KAT9 Monoclonal Souris est utilisé pour la détection de ELP3/KAT9 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour ELP3/KAT9 anticorps (C-Term) (HRP) (ABIN7987405)

Antigène: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ELP3/KAT9 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 8B4

Détail du produit anti-ELP3/KAT9 anticorps (HRP)

Épitope: C-Term

Fonction: Anti-KAT9/ELP3 Antibody (monoclonal, 8B4) HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse sequence.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human KAT9/ELP3, identical to the related mouse sequence.

Isotype: IgG2a

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ELP3/KAT9

Antigène: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Autre désignation: ELP3

Sujet:

Background: Elongator complex protein 3, also named KAT9, is aproteinthat in humans is encoded by theELP3gene. It is mapped to 8p21.1. ELP3 is the catalytichistone acetyltransferasesubunit of theRNA polymeraseII elongator complex, which is a component of the RNA polymerase II (Pol II)holoenzymeand is involved in transcriptional elongation. ELP3 supports the migration and branching ofprojection neuronsthroughacetylationof alpha-tubulin in the developingcerebral cortex. In mammals, ELP3 is important for paternalDNA demethylationafterfertilization.ELP3 is potentially involved in cellular redoxhomeostasisby mediating the acetylation ofglucose-6-phosphate dehydrogenase. Besides, ELP3 may play a role inchromatin remodelingand is involved in acetylation ofhistones H3and probablyH4.

Gene Full Name: elongator acetyltransferase complex subunit 3

ID gène: 55140

UniProt: Q9H9T3