ELP3/KAT9 anticorps (C-Term)

N° du produit ABIN7987409

Cet anticorps anti-ELP3/KAT9 Monoclonal Souris (Clone 8B4) (ABIN7987409) détecte spécifiquement ELP3/KAT9 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ELP3/KAT9 anticorps (C-Term) (ABIN7987409)

Antigène: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ELP3/KAT9 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Clone: 8B4

Détail du produit anti-ELP3/KAT9 anticorps

Épitope: C-Term

Fonction: Anti-KAT9/ELP3 Antibody (monoclonal, 8B4)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse sequence.

Attributs du produit: Anti-KAT9/ELP3 Antibody.(monoclonal, 8B4)-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human KAT9/ELP3, identical to the related mouse sequence.

Isotype: IgG2a

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ELP3/KAT9

Antigène: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Autre désignation: ELP3

Sujet:

Background: Elongator complex protein 3, also named KAT9, is aproteinthat in humans is encoded by theELP3gene. It is mapped to 8p21.1. ELP3 is the catalytichistone acetyltransferasesubunit of theRNA polymeraseII elongator complex, which is a component of the RNA polymerase II (Pol II)holoenzymeand is involved in transcriptional elongation. ELP3 supports the migration and branching ofprojection neuronsthroughacetylationof alpha-tubulin in the developingcerebral cortex. In mammals, ELP3 is important for paternalDNA demethylationafterfertilization.ELP3 is potentially involved in cellular redoxhomeostasisby mediating the acetylation ofglucose-6-phosphate dehydrogenase. Besides, ELP3 may play a role inchromatin remodelingand is involved in acetylation ofhistones H3and probablyH4.

Gene Full Name: elongator acetyltransferase complex subunit 3

Poids moléculaire: 62 kDa

ID gène: 55140

UniProt: Q9H9T3