EVL anticorps (AA 268-400) (APC)

N° du produit ABIN7987483

L’anticorps anti-EVL Polyclonal Lapin est utilisé pour la détection de EVL dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour EVL anticorps (AA 268-400) (APC) (ABIN7987483)

Antigène: EVL (Ena-Vasodilator Stimulated Phosphoprotein (EVL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EVL est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-EVL anticorps (APC)

Épitope: AA 268-400

Fonction: Anti-EVL Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human EVL recombinant protein (Position: M268-E400).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur EVL

Antigène: EVL (Ena-Vasodilator Stimulated Phosphoprotein (EVL))

Autre désignation: EVL

Sujet:

Background: Ena/VASP-like protein is a member of the Ena/VASP family of proteins that in humans is encoded by the EVL gene. Ena/VASP-like (EVL) protein is a member of the Ena/VASP family and is involved in actin-associated cytoskeleton remodeling and cell polarity activities including axon guidance and lamellipodia formation in migrating cells. The EVL protein sequence contains an N-terminal EVH1 domain, a Pro-rich SH3 binding domain, and a C-terminal EVH2 domain. EVL domain interactions with G- and F-actin mediates actin nucleation and polymerization. Research studies have shown that EVL also regulates DNA repair by interaction with RAD51. EVL may function in the DSB repair pathway through the EVH2 domain, which possesses DNA-binding and RAD51 binding activity, thereby coordinating homologous DNA recombination. Research studies have shown EVL expression is up-regulated in human breast cancer associated with clinical stages and may be implicated in invasion and/or metastasis of human breast cancer.

Gene Full Name: Enah/Vasp-like

ID gène: 51466

UniProt: Q9UI08