Endoglin anticorps (Middle Region)

N° du produit ABIN7987530

Cet anticorps Lapin Polyclonal détecte spécifiquement Endoglin dans WB et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Endoglin anticorps (Middle Region) (ABIN7987530)

Antigène: Endoglin (ENG)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endoglin est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-Endoglin anticorps

Épitope: Middle Region

Fonction: Anti-CD105/ENG Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by twelve amino acids.

Attributs du produit: Anti-CD105/ENG Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human CD105, different from the related mouse sequence by twelve amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: ENG

Sujet:

Background: Endoglin (Osler-Rendu-Weber syndrome 1), CD105, is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex. Its gene is mapped to human chromosome 8. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts and smooth muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregnant women who subsequently develop preeclampsia.

Gene Full Name: endoglin

Poids moléculaire: 95 kDa

ID gène: 2022

UniProt: P17813