EDC4 anticorps (AA 1082-1388) (Cy3)

N° du produit ABIN7987776

Cet anticorps Lapin Polyclonal détecte spécifiquement EDC4 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour EDC4 anticorps (AA 1082-1388) (Cy3) (ABIN7987776)

Antigène: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDC4 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-EDC4 anticorps (Cy3)

Épitope: AA 1082-1388

Fonction: Anti-EDC4 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human EDC4 recombinant protein (Position: K1082-L1388).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur EDC4

Antigène: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Autre désignation: EDC4

Sujet:

Background: Enhancer of mRNA-decapping protein 4 is a protein that in humans is encoded by the EDC4 gene. Enhancer of mRNA decapping 4 (EDC4) was originally identified as the autoantigen Ge-1 from a Sjgren's syndrome patient later diagnosed with primary biliary cirrhosis. EDC4 (also known as HEDLS) was later identified as an essential component of cytoplasmic P-bodies responsible for mRNA decapping and degradation. Identified EDC4 protein is found as a pair of isoforms generated by alternative splicing and contains several WD domains and a putative nuclear localization signal. EDC4 co-localizes with other P-body decapping proteins such as DCP1A, DCP2 and GW182. Experimental evidence suggests that EDC4 may be involved in miRNA-mediated translation repression.

Gene Full Name: enhancer of mRNA decapping 4

ID gène: 23644

UniProt: Q6P2E9