EIF1 anticorps (AA 2-10) (HRP)
Aperçu rapide pour EIF1 anticorps (AA 2-10) (HRP) (ABIN7988663)
Antigène
Voir toutes EIF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 2-10
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Fonction
- Anti-EIF1 Antibody HRP Conjugated
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human EIF1 recombinant protein (Position: S2-D106).
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Isotype
- IgG
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Indications d'application
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- EIF1 (Eukaryotic Translation Initiation Factor 1 (EIF1))
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Autre désignation
- EIF1
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Sujet
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Background: Eukaryotic translation initiation factor 1 (eIF1) is a protein that in humans is encoded by the EIF1 gene. It is related to yeast SUI1. In mammalian cells, translation is controlled at the level of polypeptide chain initiation by initiation factors. Eukaryotic translation initiation factor 1 (eIF1) is crucial for the scanning process in vitro. During the scanning process, eIF1 is a component of a complex involved in recognition of the initiator codon. Translation is also initiated by the role of eIF1 in regulating the activity of ribosomal subunits 43S, 48S and 40S. eIF1 enables 43S ribosomal complexes to discern between cognate and near-cognate initiation codons, sensing the nucleotide content of initiation codons. It is also a promotor, along with eukar-yotic translation initiation factor 1A (eIF1A), for assembly of 48S ribosomal complexes at the initiation codon of a conventional capped mRNA. In addition, eIF1 and eIF1A, together with eukaryotic translation initiation factor 5 (eIF5), function in the formation of stable 40S ribosomal preinitiation complexes.
Gene Full Name: eukaryotic translation initiation factor 1
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ID gène
- 10209
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UniProt
- P41567
Antigène
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