FBXW8 anticorps (AA 1-598) (Biotin)

N° du produit ABIN7989453

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXW8 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour FBXW8 anticorps (AA 1-598) (Biotin) (ABIN7989453)

Antigène: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW8 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-FBXW8 anticorps (Biotin)

Épitope: AA 1-598

Fonction: Anti-FBXW8 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human FBXW8 shares 78.5%,77.4% amino acid (aa) sequence identity with mouse,rat FBXW8,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FBXW8 recombinant protein (Position: M1-V598). Human FBXW8 shares 78.5% and 77.4% amino acid (aa) sequence identity with mouse and rat FBXW8, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FBXW8

Antigène: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Autre désignation: FBXW8

Sujet:

Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Gene Full Name: F-box and WD repeat domain containing 8

ID gène: 26259

UniProt: Q8N3Y1