F11R anticorps (N-Term) (Fluoro647)

N° du produit ABIN7989506

Cet anticorps anti-F11R Polyclonal Lapin conjugué à Fluoro647 (ABIN7989506) détecte spécifiquement F11R dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour F11R anticorps (N-Term) (Fluoro647) (ABIN7989506)

Antigène: F11R (F11 Receptor (F11R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F11R est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-F11R anticorps (Fluoro647)

Épitope: N-Term

Fonction: Anti-JAM-A/F11R Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human JAM-A/F11R, which shares 75% and 80% amino acid (aa) sequence identity with mouse and rat JAM-A/F11R, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur F11R

Antigène: F11R (F11 Receptor (F11R))

Autre désignation: F11R

Sujet:

Background: Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Gene Full Name: F11 receptor

ID gène: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization