F11R anticorps (AA 28-294) (HRP)

N° du produit ABIN7989514

L’anticorps anti-F11R Polyclonal Lapin est utilisé pour la détection de F11R dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour F11R anticorps (AA 28-294) (HRP) (ABIN7989514)

Antigène: F11R (F11 Receptor (F11R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F11R est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-F11R anticorps (HRP)

Épitope: AA 28-294

Fonction: Anti-JAM-A/F11R Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human JAM-A/F11R recombinant protein (Position: S28-T294).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur F11R

Antigène: F11R (F11 Receptor (F11R))

Autre désignation: F11R

Sujet:

Background: Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Gene Full Name: F11 receptor

ID gène: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization