FTO anticorps (AA 279-505) (Fluoro550)
Aperçu rapide pour FTO anticorps (AA 279-505) (Fluoro550) (ABIN7989798)
Antigène
Voir toutes FTO AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 279-505
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Fonction
- Anti-FTO Antibody Fluoro550 Conjugated
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human FTO recombinant protein (Position: D279-P505).
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Isotype
- IgG
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Indications d'application
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Date de péremption
- 12 months
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- FTO (Fat Mass and Obesity-Associated (FTO))
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Autre désignation
- FTO
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Sujet
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Background: Fat mass and obesity-associated protein also known as alpha-ketoglutarate-dependent dioxygenase FTO is an enzyme that in humans is encoded by the FTO gene located on chromosome 16. This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Gene Full Name: FTO alpha-ketoglutarate dependent dioxygenase
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ID gène
- 79068
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UniProt
- Q9C0B1
Antigène
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