FERMT2 anticorps (AA 1-650) (Cy3)

N° du produit ABIN7990258

L’anticorps anti-FERMT2 Polyclonal Lapin est utilisé pour la détection de FERMT2 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour FERMT2 anticorps (AA 1-650) (Cy3) (ABIN7990258)

Antigène: FERMT2 (Fermitin Family Member 2 (FERMT2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FERMT2 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-FERMT2 anticorps (Cy3)

Épitope: AA 1-650

Fonction: Anti-Kindlin 2/FERMT2 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Kindlin 2/FERMT2 recombinant protein (Position: M1-I650).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur FERMT2

Antigène: FERMT2 (Fermitin Family Member 2 (FERMT2))

Autre désignation: FERMT2

Sujet:

Background: Fermitin family homolog 2 (FERMT2) also known as pleckstrin homology domain-containing family C member 1 (PLEKHC1) or kindlin-2 is a protein that in humans is encoded by the FERMT2 gene. Enables several functions, including actin binding activity, phosphatidylinositol-3,4,5-trisphosphate binding activity, and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway, positive regulation of cell differentiation, and positive regulation of cellular component biogenesis. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in cytosol, focal adhesion, and nucleoplasm. Is extrinsic component of cytoplasmic side of plasma membrane. Part of adherens junction and plasma membrane. Biomarker of acute myeloid leukemia.

Gene Full Name: FERM domain containing kindlin 2

ID gène: 10979

UniProt: Q96AC1

Pathways: Cell-Cell Junction Organization