FLNB anticorps (AA 397-701) (Biotin)

N° du produit ABIN7990897

L’anticorps anti-FLNB Monoclonal Souris est utilisé pour la détection de FLNB dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour FLNB anticorps (AA 397-701) (Biotin) (ABIN7990897)

Antigène: FLNB (Filamin B, beta (FLNB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FLNB est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 11E2D2

Détail du produit anti-FLNB anticorps (Biotin)

Épitope: AA 397-701

Fonction: Anti-Filamin B/FLNB Antibody (monoclonal, 11E2D2) Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Filamin B/FLNB recombinant protein (Position: Q397-D701).

Isotype: IgG1

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FLNB

Antigène: FLNB (Filamin B, beta (FLNB))

Autre désignation: FLNB

Sujet:

Background: Filamin B, beta (FLNB), also known as Filamin B, beta (truncated actin binding protein 278 homolog), is a cytoplasmic protein which in humans is encoded by the FLNB gene. This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene Full Name: filamin B

ID gène: 2317

UniProt: O75369

Pathways: Maintenance of Protein Location