Fission 1 anticorps (AA 18-152) (Biotin)

N° du produit ABIN7990930

L’anticorps anti-Fission 1 Polyclonal Lapin est utilisé pour la détection de Fission 1 dans des échantillons de Humain et Rat. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour Fission 1 anticorps (AA 18-152) (Biotin) (ABIN7990930)

Antigène: Fission 1 (FIS1)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fission 1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Fission 1 anticorps (Biotin)

Épitope: AA 18-152

Fonction: Anti-TTC11/FIS1 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TTC11/FIS1 recombinant protein (Position: E18-S152).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Fission 1

Antigène: Fission 1 (FIS1)

Autre désignation: FIS1

Sujet:

Background: Mitochondrial fission 1 protein (FIS1) is a protein that in humans is encoded by the FIS1 gene on chromosome 7. It is mapped to 7q22.1. The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. Its role in mitochondrial fission thus implicates it in the regulation of mitochondrial morphology, the cell cycle, and apoptosis. By extension, the protein is involved in associated diseases, including neurodegenerative diseases and cancers.

Gene Full Name: fission, mitochondrial 1

ID gène: 51024

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity