GATA3 anticorps (AA 1-197) (Fluoro647)

N° du produit ABIN7992947

Cet anticorps anti-GATA3 Polyclonal Lapin conjugué à Fluoro647 (ABIN7992947) détecte spécifiquement GATA3 dans FACS. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour GATA3 anticorps (AA 1-197) (Fluoro647) (ABIN7992947)

Antigène: GATA3 (GATA Binding Protein 3 (GATA3))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATA3 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-GATA3 anticorps (Fluoro647)

Épitope: AA 1-197

Fonction: Anti-GATA3 Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human GATA3 shares 95% amino acid (aa) sequence identity with mouse GATA3.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GATA3 recombinant protein (Position: M1-E197). Human GATA3 shares 95% amino acid (aa) sequence identity with mouse GATA3.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur GATA3

Antigène: GATA3 (GATA Binding Protein 3 (GATA3))

Autre désignation: GATA3

Sujet:

Background: Trans-acting T-cell-specific transcription factor GATA-3, also named HDR or GATA3, is a protein that in humans is encoded by the GATA3 gene. It is mapped to 10p14. This gene belongs to the GATA family of transcription factors. It regulates luminal epithelial cell differentiation in the mammary gland. The protein contains two GATA-type zinc fingers, it is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells, and induces the differentiation of Th0 cells towards this T cell subtype while suppressing their differentiation towards Th1 cells.

Gene Full Name: GATA binding protein 3

Sequence Similarities: Contains 2 GATA-type zinc fingers.

ID gène: 2625

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation