GATA3 anticorps (N-Term) (Fluoro488)
Aperçu rapide pour GATA3 anticorps (N-Term) (Fluoro488) (ABIN7992951)
Antigène
Voir toutes GATA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- Anti-GATA3 Antibody Fluoro488 Conjugated
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the N-terminus of human GATA3, which shares 86.4% and 90.9% amino acid (aa) sequence identity with mouse and rat GATA3, respectively.
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Isotype
- IgG
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Indications d'application
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Date de péremption
- 12 months
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- GATA3 (GATA Binding Protein 3 (GATA3))
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Autre désignation
- GATA3
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Sujet
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Background: Trans-acting T-cell-specific transcription factor GATA-3, also named HDR or GATA3, is a protein that in humans is encoded by the GATA3 gene. It is mapped to 10p14. This gene belongs to the GATA family of transcription factors. It regulates luminal epithelial cell differentiation in the mammary gland. The protein contains two GATA-type zinc fingers, it is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells, and induces the differentiation of Th0 cells towards this T cell subtype while suppressing their differentiation towards Th1 cells.
Gene Full Name: GATA binding protein 3
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ID gène
- 2625
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UniProt
- P23771
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Pathways
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
Antigène
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