GATA5 anticorps (AA 1-397) (Biotin)

N° du produit ABIN7992971

Cet anticorps anti-GATA5 Polyclonal Lapin conjugué à Biotin (ABIN7992971) détecte spécifiquement GATA5 dans ELISA, WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GATA5 anticorps (AA 1-397) (Biotin) (ABIN7992971)

Antigène: GATA5 (GATA Binding Protein 5 (GATA5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATA5 est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GATA5 anticorps (Biotin)

Épitope: AA 1-397

Fonction: Anti-GATA5 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human GATA5 shares 75% amino acid (aa) sequence identity with mouse GATA5.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GATA5 recombinant protein (Position: M1-A397). Human GATA5 shares 75% amino acid (aa) sequence identity with mouse GATA5.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GATA5

Antigène: GATA5 (GATA Binding Protein 5 (GATA5))

Autre désignation: GATA5

Sujet:

Background: Transcription factor GATA-5, also named GATAS or GATA5, is a protein that in humans is encoded by the GATA5 gene. It is mapped to 20q13.33. The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. In addition, the expression of GATA5 increased in a human colon cancer cell line within 2 hours of exposure to sodium butyrate, which induces differentiation.

Gene Full Name: GATA binding protein 5

Sequence Similarities: Contains 2 GATA-type zinc fingers.

ID gène: 140628

UniProt: Q9BWX5