TREM2 anticorps (AA 1-100)

N° du produit ABIN749678

3+ publications sont disponibles pour ce produit. L’anticorps anti-TREM2 Polyclonal produit chez le Lapin a été validé pour WB, ELISA, ICC, IHC (p), IHC (fro), IF (p) et IF (cc). Il convient pour la détection de TREM2 dans des échantillons provenant de Souris, Humain, Rat et Porc. }

Aperçu rapide pour TREM2 anticorps (AA 1-100) (ABIN749678)

Antigène: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reactivité: Souris, Humain, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TREM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-TREM2 anticorps

Épitope: AA 1-100

Réactivité croisée: Humain, Souris, Porc, Rat

Homologie: Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TREM2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TREM2 (ABIN749678)

Abdi, Pasbakhsh, Shabani, Nekoonam, Sadeghi, Fathi, Abouzaripour, Mohamed, Zibara, Kashani, Zendedel: "Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis." dans: Neurotoxicity research, (2021) (PubMed).

Rai, Dietz, Dilisio, Radwan, Agrawal: "Vitamin D attenuates inflammation, fatty infiltration, and cartilage loss in the knee of hyperlipidemic microswine." dans: Arthritis research & therapy, Vol. 18, Issue 1, pp. 203, (2016) (PubMed).

Satoh, Kawana, Yamamoto, Ishida, Saito, Arima: "A survey of TREM2 antibodies reveals neuronal but not microglial staining in formalin-fixed paraffin-embedded postmortem Alzheimer's brain tissues." dans: Alzheimer's research & therapy, Vol. 5, Issue 4, pp. 30, (2014) (PubMed).

Détails sur TREM2

Antigène: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Autre désignation: TREM2

Sujet:

Synonyms: TREM-2, Trem2a, Trem2b, Trem2c, Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM2

Background: May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.

ID gène: 54209

UniProt: Q9NZC2