GBA3 anticorps (AA 17-469) (HRP)

N° du produit ABIN7993549

L’anticorps anti-GBA3 Polyclonal Lapin est utilisé pour la détection de GBA3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour GBA3 anticorps (AA 17-469) (HRP) (ABIN7993549)

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBA3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GBA3 anticorps (HRP)

Épitope: AA 17-469

Fonction: Anti-GBA3 Antibody HRP Conjugated

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GBA3 recombinant protein (Position: Q17-L469).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GBA3

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Autre désignation: GBA3

Sujet:

Background: Cytosolic beta-glucosidase, also known as cytosolic beta-glucosidase-like protein 1, is a beta-glucosidase (EC 3.2.1.21) enzyme that in humans is encoded by the GBA3 gene. The protein encoded by this gene is a cytosolic enzyme that can hydrolyze several types of glycosides. The enzyme has its highest activity at neutral pH and is predominantly expressed in human liver, kidney, intestine, and spleen. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: glucosylceramidase beta 3 (gene/pseudogene)

ID gène: 57733

UniProt: Q9H227