Glutamate Receptor 1 anticorps (AA 19-360) (Fluoro647)

N° du produit ABIN7993684

L’anticorps anti-Glutamate Receptor 1 Polyclonal Lapin est utilisé pour la détection de Glutamate Receptor 1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour Glutamate Receptor 1 anticorps (AA 19-360) (Fluoro647) (ABIN7993684)

Antigène: Glutamate Receptor 1 (GLUR1)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutamate Receptor 1 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-Glutamate Receptor 1 anticorps (Fluoro647)

Épitope: AA 19-360

Fonction: Anti-Glutamate Receptor 1/GRIA1 Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human GRIA1 shares 98% amino acid (aa) sequence identity with both mouse,rat GRIA1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GRIA1 recombinant protein (Position: A19-R360). Human GRIA1 shares 98% amino acid (aa) sequence identity with both mouse and rat GRIA1.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Glutamate Receptor 1

Antigène: Glutamate Receptor 1 (GLUR1)

Autre désignation: GRIA1

Sujet:

Background: GLUR1, Glutamate receptor 1, is a protein that in humans is encoded by the GLUR1 gene. GLUR1 mRNA is widely expressed in human brain. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties. The isoform presented here is the flop isoform. In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation.

Gene Full Name: glutamate ionotropic receptor AMPA type subunit 1

ID gène: 2890

UniProt: P42261

Pathways: Signalisation PI3K-Akt