GPT2 anticorps (AA 56-523) (HRP)
Aperçu rapide pour GPT2 anticorps (AA 56-523) (HRP) (ABIN7993958)
Antigène
Voir toutes GPT2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 56-523
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Fonction
- Anti-GPT2 Antibody HRP Conjugated
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Human GPT2 shares 94.4% amino acid (aa) sequence identity with mouse GPT2.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human GPT2 recombinant protein (Position: Q56-A523). Human GPT2 shares 94.4% amino acid (aa) sequence identity with mouse GPT2.
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Isotype
- IgG
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Indications d'application
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- GPT2 (Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2))
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Autre désignation
- GPT2
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Sujet
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Background: This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.
Gene Full Name: glutamic--pyruvic transaminase 2
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ID gène
- 84706
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UniProt
- Q8TD30
Antigène
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