Glutaredoxin 1 anticorps (AA 1-106) (HRP)

N° du produit ABIN7994091

Cet anticorps Lapin Polyclonal détecte spécifiquement Glutaredoxin 1 dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Glutaredoxin 1 anticorps (AA 1-106) (HRP) (ABIN7994091)

Antigène: Glutaredoxin 1 (GRX1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutaredoxin 1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Glutaredoxin 1 anticorps (HRP)

Épitope: AA 1-106

Fonction: Anti-Glutaredoxin 1/GLRX Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Glutaredoxin 1/GLRX recombinant protein (Position: M1-Q106).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Glutaredoxin 1

Antigène: Glutaredoxin 1 (GRX1)

Autre désignation: GLRX

Sujet:

Background: Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene. This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Gene Full Name: glutaredoxin

ID gène: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis