GSTA1 anticorps (AA 2-222)

N° du produit ABIN7994249

Cet anticorps anti-GSTA1 Polyclonal Lapin (ABIN7994249) détecte spécifiquement GSTA1 dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GSTA1 anticorps (AA 2-222) (ABIN7994249)

Antigène: GSTA1 (Glutathione S-Transferase alpha 1 (GSTA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTA1 est non-conjugé

Application: ELISA

Classe de qualité: Carrier-free

Détail du produit anti-GSTA1 anticorps

Épitope: AA 2-222

Fonction: Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody. Tested in ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived humn GSTA1/A2/A3/A4/A5 recombinant protein (Position: A2-F222).

Isotype: IgG

Information d'application

Indications d'application: ELISA Capture (Matched Antibody Pair), 2-8 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GSTA1

Antigène: GSTA1 (Glutathione S-Transferase alpha 1 (GSTA1))

Autre désignation: GSTA1

Sujet:

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules). In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity, thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Gene Full Name: glutathione S-transferase alpha 1

Poids moléculaire: 26 kDa

ID gène: 2938

UniProt: P08263